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Santee cooper resort Santee currently has 4 properties for sale listed on MLS. Santee cooper resort properties have an average sq foot of 2,569. All the MLS Listings in Santee cooper resort are 4, are priced from $334,900 to $848,000 with an average median home for sale priced around $513,225. The highest square foot 3,300 to the lowest at 2,236.